Details

Autor(en) / Beteiligte

• Ngo, Ha-Hien-Phuong
• Andrade, Ricardo
• Brum, Javier
• Benech, Nicolas
• Chatelin, Simon
• Loumeaud, Aude
• Frappart, Thomas
• Fraschini, Christophe
• Nordez, Antoine
• Gennisson, Jean-Luc

Titel

In plane quantification of in vivo muscle elastic anisotropy factor by steered ultrasound pushing beams

Ist Teil von

• Physics in medicine & biology, 2024-02, Vol.69 (4), p.45013

Ort / Verlag

England: IOP Publishing

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Skeletal muscles are organized into distinct layers and exhibit anisotropic characteristics across various scales. Assessing the arrangement of skeletal muscles may provide valuable biomarkers for diagnosing muscle-related pathologies and evaluating the efficacy of clinical interventions. . In this study, we propose a novel ultrafast ultrasound sequence constituted of steered pushing beams was proposed for ultrasound elastography applications in transverse isotropic muscle. Based on the propagation of the shear wave vertical mode, it is possible to fit the experimental results to retrieve in the same imaging plane, the shear modulus parallel to fibers as well as the elastic anisotropy factor (ratio of Young's moduli times the shear modulus perpendicular to fibers). . The technique was demonstrated in phantoms and in fusiform beef muscles. At last, the technique was applied on fusiform muscles ( ) and mono-pennate muscles ( ) during stretching and contraction. . This novel sequence provides access to new structural and mechanical biomarkers of muscle tissue, including the elastic anisotropy factor, within the same imaging plane. Additionally, it enables the investigation of multiples parameters during muscle active and passive length changes.