Details

Autor(en) / Beteiligte

• Ouafek, N.
• Keghouche, N.
• Beaunier, P.
• Belloni, J.
• Mostafavi, M.

Titel

Antibacterial activity of intermetallic NixMgy and NiO–MgO phases in nickel-magnesium oxide nanocomposites

Ist Teil von

• Radiation physics and chemistry (Oxford, England : 1993), 2023-01, Vol.202, p.110499, Article 110499

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• This work focuses on Ni–Mg metallic nanomaterials and NiO–MgO composites, especially on their antibacterial activity against Escherichia coli (E. coli(G-)) and Staphylococcus aureus (S. aureus(G+)) in relation with their size and structure. They are generated by impregnation of nickel formate, followed by either calcination (T = 100–600 °C) or gamma-irradiation at room temperature. In samples prepared by calcination at temperatures T ≤ 300 °C or irradiation, the structural study by XRD and HRTEM reveals the presence of nanoscaled Ni–Mg intermetallic phases: NiMg2, Ni2Mg and NiMg6.33 (2–4 nm diameter) and magnesium hydroxide Mg(OH)2. At T > 300 °C, only the NiO–MgO solid solution is formed. Bare MgO and NiO–MgO nanoparticles exhibit a bacterial activity only against E. coli and S. aureus, respectively. In contrast, the Ni–Mg intermetallic phases of high specific area, that are present in irradiated (T = 20 °C) or calcined (T ≤ 300 °C) samples, exhibit a significant antibacterial activity against both E. coli and S. aureus. •Irradiation (20 °C) or calcination of Ni2+/MgO give rise to intermetallic NixMgy.•Ni2+ ions are reduced into Ni clusters in presence of formate under basic conditions.•Ni/MgO samples calcined at T = 300 °C display a large specific area (93.3 m2 g−1).•The toxicity against S. aureus and E.coli is due to a synergistic effect of Ni and Mg.