Details

Autor(en) / Beteiligte

• Macquet, Joris
• Mounichetty, Shantala
• Raffaele, Sylvain

Titel

Genetic co-option into plant–filamentous pathogen interactions

Ist Teil von

• Trends in plant science, 2022-11, Vol.27 (11), p.1144-1158

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2022

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Plants are engaged in a coevolutionary arms race with their pathogens that drives rapid diversification and specialization of genes involved in resistance and virulence. However, some major innovations in plant–pathogen interactions, such as molecular decoys, trans-kingdom RNA interference, two-speed genomes, and receptor networks, evolved through the expansion of the functional landscape of genes. This is a typical outcome of genetic co-option, the evolutionary process by which available genes are recruited into new biological functions. Co-option into plant–pathogen interactions emerges generally from (i) cis-regulatory variation, (ii) horizontal gene transfer (HGT), (iii) mutations altering molecular promiscuity, and (iv) rewiring of gene networks and protein complexes. Understanding these molecular mechanisms is key for the functional and predictive biology of plant–pathogen interactions. The coevolution of plants and their filamentous pathogens shapes elaborate molecular mechanisms for survival and manipulation.Recent studies have revealed that the evolution of several key innovations, both in plant defense and pathogen virulence, involved the co-option of pre-existing genetic components, adding new functions to old ones.Co-option by regulatory and mobile genetic elements has recruited new genes for defense and virulence, enabling concerted gene activation and trans-kingdom manipulation of gene expression.The diversification of plant disease resistance and pathogen effector proteins involves the reshuffling and repurposing of existing protein domains and protein family members.