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Intravascular Complications of Central Venous Catheterization by Insertion Site
Ist Teil von
The New England journal of medicine, 2015-09, Vol.373 (13), p.1220-1229
Ort / Verlag
United States: Massachusetts Medical Society
Erscheinungsjahr
2015
Quelle
MEDLINE
Beschreibungen/Notizen
Patients in the ICU were assigned to catheter insertion in the subclavian, jugular, or femoral vein. Subclavian catheterization had a lower risk of bloodstream infection and deep-vein thrombosis, and a higher risk of pneumothorax, than catheterization in the other two sites.
Subclavian, jugular, and femoral central venous catheterization are associated with infectious, thrombotic, and mechanical complications.
1
Catheter-related bloodstream infection has a significant effect on morbidity, mortality, and health care costs.
2
–
4
The risk of short-term catheter-related bloodstream infection is influenced mainly by extraluminal microbial colonization of the insertion site,
5
and such colonization is also associated with thrombosis.
6
,
7
Although the importance of catheter-related deep-vein thrombosis has been debated,
1
all thromboses have the potential to embolize. In addition, catheter-related deep-vein thrombosis
7
–
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and pulmonary embolism
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may remain undiagnosed in critically ill patients undergoing mechanical ventilation.
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We conducted the 3SITES multicenter study to . . .