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Efficacy of Chest CT for COVID-19 Pneumonia Diagnosis in France
Radiology, 2021-02, Vol.298 (2), p.E81-E87
Herpe, Guillaume
Lederlin, Mathieu
Naudin, Mathieu
Ohana, Mickaël
Chaumoitre, Kathia
Gregory, Jules
Vilgrain, Valérie
Freitag, Cornelia Anna
De Margerie-Mellon, Constance
Flory, Violaine
Ludwig, Marie
Mondot, Lydiane
Fitton, Isabelle
Jacquier, Alexis Raymond Robert
Ardilouze, Paul
Petit, Isabelle
Gervaise, Alban
Bayle, Olivier
Crombe, Arielle
Mekuko Sokeng, Magloire
Thomas, Clément
Henry, Geraldine
Bliah, Virginie
Le Tat, Thomas
Guillot, Marc-Samir
Gendrin, Paul
Garetier, Marc
Bertolle, Estelle
Montagne, Catherine
Langlet, Benjamin
Kalaaji, Abdulrazak
Kayayan, Hampar
Desmots, Florian
Dhaene, Benjamin
Saulnier, Pierre-Jean
Guillevin, Remy
Bartoli, Jean-Michel
Beregi, Jean-Paul
Tasu, Jean Pierre
2021
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Herpe, Guillaume
Lederlin, Mathieu
Naudin, Mathieu
Ohana, Mickaël
Chaumoitre, Kathia
Gregory, Jules
Vilgrain, Valérie
Freitag, Cornelia Anna
De Margerie-Mellon, Constance
Flory, Violaine
Ludwig, Marie
Mondot, Lydiane
Fitton, Isabelle
Jacquier, Alexis Raymond Robert
Ardilouze, Paul
Petit, Isabelle
Gervaise, Alban
Bayle, Olivier
Crombe, Arielle
Mekuko Sokeng, Magloire
Thomas, Clément
Henry, Geraldine
Bliah, Virginie
Le Tat, Thomas
Guillot, Marc-Samir
Gendrin, Paul
Garetier, Marc
Bertolle, Estelle
Montagne, Catherine
Langlet, Benjamin
Kalaaji, Abdulrazak
Kayayan, Hampar
Desmots, Florian
Dhaene, Benjamin
Saulnier, Pierre-Jean
Guillevin, Remy
Bartoli, Jean-Michel
Beregi, Jean-Paul
Tasu, Jean Pierre
Titel
Efficacy of Chest CT for COVID-19 Pneumonia Diagnosis in France
Ist Teil von
Radiology, 2021-02, Vol.298 (2), p.E81-E87
Ort / Verlag
United States: Radiological Society of North America
Erscheinungsjahr
2021
Quelle
Free E-Journal (出版社公開部分のみ)
Beschreibungen/Notizen
Background The role and performance of chest CT in the diagnosis of the coronavirus disease 2019 (COVID-19) pandemic remains under active investigation. Purpose To evaluate the French national experience using chest CT for COVID-19, results of chest CT and reverse transcription polymerase chain reaction (RT-PCR) assays were compared together and with the final discharge diagnosis used as the reference standard. Materials and Methods A structured CT scan survey (NCT04339686) was sent to 26 hospital radiology departments in France between March 2, 2020, and April 24, 2020. These dates correspond to the peak of the national COVID-19 epidemic. Radiology departments were selected to reflect the estimated geographic prevalence heterogeneities of the epidemic. All symptomatic patients suspected of having COVID-19 pneumonia who underwent both initial chest CT and at least one RT-PCR test within 48 hours were included. The final discharge diagnosis, based on multiparametric items, was recorded. Data for each center were prospectively collected and gathered each week. Test efficacy was determined by using the Mann-Whitney test, Student test, χ test, and Pearson correlation coefficient. < .05 indicated a significant difference. Results Twenty-six of 26 hospital radiology departments responded to the survey, with 7500 patients entered; 2652 did not have RT-PCR test results or had unknown or excess delay between the RT-PCR test and CT. After exclusions, 4824 patients (mean age, 64 years ± 19 [standard deviation], 2669 male) were included. With final diagnosis as the reference, 2564 of the 4824 patients had COVID-19 (53%). Sensitivity, specificity, negative predictive value, and positive predictive value of chest CT in the diagnosis of COVID-19 were 2319 of 2564 (90%; 95% CI: 89, 91), 2056 of 2260 (91%; 95% CI: 91, 92), 2056 of 2300 (89%; 95% CI: 87, 90), and 2319 of 2524 (92%; 95% CI: 91, 93), respectively. There was no significant difference for chest CT efficacy among the 26 geographically separate sites, each with varying amounts of disease prevalence. Conclusion Use of chest CT for the initial diagnosis and triage of patients suspected of having coronavirus disease 2019 was successful. © RSNA, 2021
Sprache
Englisch
Identifikatoren
ISSN: 0033-8419, 1527-1315
eISSN: 1527-1315
DOI: 10.1148/RADIOL.2020202568
Titel-ID: cdi_hal_primary_oai_HAL_hal_03570653v1
Format
–
Schlagworte
Adolescent
,
Adult
,
Aged
,
Aged, 80 and over
,
Child
,
Child, Preschool
,
Computer Science
,
COVID-19 - diagnostic imaging
,
COVID-19 - epidemiology
,
Female
,
France - epidemiology
,
Human health and pathology
,
Humans
,
Life Sciences
,
Male
,
Medical Imaging
,
Middle Aged
,
Prospective Studies
,
Pulmonology and respiratory tract
,
Radiography, Thoracic - methods
,
SARS-CoV-2
,
Sensitivity and Specificity
,
Tomography, X-Ray Computed - methods
,
Young Adult
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