Details

Autor(en) / Beteiligte

• Thompson, Alexis A
• Walters, Mark C
• Kwiatkowski, Janet
• Rasko, John E.J
• Ribeil, Jean-Antoine
• Hongeng, Suradej
• Magrin, Elisa
• Schiller, Gary J
• Payen, Emmanuel
• Semeraro, Michaela
• Moshous, Despina
• Lefrere, Francois
• Puy, Hervé
• Bourget, Philippe
• Magnani, Alessandra
• Caccavelli, Laure
• Diana, Jean-Sébastien
• Suarez, Felipe
• Monpoux, Fabrice
• Brousse, Valentine
• Poirot, Catherine
• Brouzes, Chantal
• Meritet, Jean-François
• Pondarré, Corinne
• Beuzard, Yves
• Chrétien, Stany
• Lefebvre, Thibaud
• Teachey, David T
• Anurathapan, Usanarat
• Ho, P. Joy
• von Kalle, Christof
• Kletzel, Morris
• Vichinsky, Elliott
• Soni, Sandeep
• Veres, Gabor
• Negre, Olivier
• Ross, Robert W
• Davidson, David
• Petrusich, Alexandria
• Sandler, Laura
• Asmal, Mohammed
• Hermine, Olivier
• De Montalembert, Mariane
• Hacein-Bey-Abina, Salima
• Blanche, Stéphane
• Leboulch, Philippe
• Cavazzana, Marina

Titel

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia

Ist Teil von

• The New England journal of medicine, 2018-04, Vol.378 (16), p.1479-1493

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2018

Quelle

MEDLINE

Beschreibungen/Notizen

• Gene therapy with CD34+ cells transduced with a lentivirus vector carrying a β-globin gene was performed in 22 patients. At a median of 26 months, all the patients were either transfusion-independent or had a major reduction in transfusion requirements.