Details

Autor(en) / Beteiligte

• COUTROT, Frédéric
• GRISON, Claude
• COUTROT, Philippe

Titel

A route to new galactosyl peptides: application to the synthesis of a galactosyl pentapeptide analogue of leu-enkephalin

Ist Teil von

• Comptes rendus. Chimie, 2004, Vol.7 (1), p.3-13

Ort / Verlag

Paris: Elsevier

Erscheinungsjahr

2004

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The syntheses of a new galactosyl alpha-amino acid building block and modified peptides including this moiety are described. The versatility of the method is illustrated by the preparation of a galactosyl pentapeptide analogue of Leu-enkephalin. Conformational studies of dipeptide models in the galactose series show an intramolecular hydrogen bond interaction between the backbone and the galactosyl side chain of the models.