Details

Autor(en) / Beteiligte

• Faroux, Laurent
• Lhermusier, Thibault
• Vincent, Flavien
• Nombela-Franco, Luis
• Tchétché, Didier
• Barbanti, Marco
• Abdel-Wahab, Mohamed
• Windecker, Stephan
• Auffret, Vincent
• Campanha-Borges, Diego Carter
• Fischer, Quentin
• Muñoz-Garcia, Erika
• Trillo-Nouche, Ramiro
• Jorgensen, Troels
• Serra, Vicens
• Toggweiler, Stefan
• Tarantini, Giuseppe
• Saia, Francesco
• Durand, Eric
• Donaint, Pierre
• Gutierrez-Ibanes, Enrique
• Wijeysundera, Harindra C
• Veiga, Gabriela
• Patti, Giuseppe
• D'Ascenzo, Fabrizio
• Moreno, Raul
• Hengstenberg, Christian
• Chamandi, Chekrallah
• Asmarats, Lluis
• Hernandez-Antolin, Rosana
• Gomez-Hospital, Joan Antoni
• Cordoba-Soriano, Juan Gabriel
• Landes, Uri
• Jimenez-Diaz, Victor Alfonso
• Cruz-Gonzalez, Ignacio
• Nejjari, Mohammed
• Roubille, François
• Van Belle, Éric
• Armijo, German
• Siddiqui, Saifullah
• Costa, Giuliano
• Elsaify, Sameh
• Pilgrim, Thomas
• le Breton, Hervé
• Urena, Marina
• Muñoz-Garcia, Antonio Jesus
• Sondergaard, Lars
• Bach-Oller, Montserrat
• Fraccaro, Chiara
• Eltchaninoff, Hélène
• Metz, Damien
• Tamargo, Maria
• Fradejas-Sastre, Victor
• Rognoni, Andrea
• Bruno, Francesco
• Goliasch, Georg
• Santaló-Corcoy, Marcelo
• Jimenez-Mazuecos, Jesus
• Webb, John G
• Muntané-Carol, Guillem
• Paradis, Jean-Michal
• Mangieri, Antonio
• Ribeiro, Henrique Barbosa
• Campelo-Parada, Francisco
• Rodés-Cabau, Josep

Titel

ST-Segment Elevation Myocardial Infarction Following Transcatheter Aortic Valve Replacement

Ist Teil von

• Journal of the American College of Cardiology, 2021-05, Vol.77 (17), p.2187-2199

Ort / Verlag

United States: Elsevier B.V

Erscheinungsjahr

2021

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Among patients with acute coronary syndrome following transcatheter aortic valve replacement (TAVR), those presenting with ST-segment elevation myocardial infarction (STEMI) are at highest risk. The goal of this study was to determine the clinical characteristics, management, and outcomes of STEMI after TAVR. This was a multicenter study including 118 patients presenting with STEMI at a median of 255 days (interquartile range: 9 to 680 days) after TAVR. Procedural features of STEMI after TAVR managed with primary percutaneous coronary intervention (PCI) were compared with all-comer STEMI: 439 non-TAVR patients who had primary PCI within the 2 weeks before and after each post-TAVR STEMI case in 5 participating centers from different countries. Median door-to-balloon time was higher in TAVR patients (40 min [interquartile range: 25 to 57 min] vs. 30 min [interquartile range: 25 to 35 min]; p = 0.003). Procedural time, fluoroscopy time, dose-area product, and contrast volume were also higher in TAVR patients (p < 0.01 for all). PCI failure occurred more frequently in patients with previous TAVR (16.5% vs. 3.9%; p < 0.001), including 5 patients in whom the culprit lesion was not revascularized owing to coronary ostia cannulation failure. In-hospital and late (median of 7 months [interquartile range: 1 to 21 months]) mortality rates were 25.4% and 42.4%, respectively (20.6% and 38.2% in primary PCI patients), and estimated glomerular filtration rate <60 ml/min (hazard ratio [HR]: 3.02; 95% confidence interval [CI]: 1.42 to 6.43; p = 0.004), Killip class ≥2 (HR: 2.74; 95% CI: 1.37 to 5.49; p = 0.004), and PCI failure (HR: 3.23; 95% CI: 1.42 to 7.31; p = 0.005) determined an increased risk. STEMI after TAVR was associated with very high in-hospital and mid-term mortality. Longer door-to-balloon times and a higher PCI failure rate were observed in TAVR patients, partially due to coronary access issues specific to the TAVR population, and this was associated with poorer outcomes.