Details

Autor(en) / Beteiligte

• Costa, Damien
• Razakandrainibe, Romy
• Sautour, Marc
• Valot, Stéphane
• Basmaciyan, Louise
• Gargala, Gilles
• Lemeteil, Denis
• Debourgogne, Anne
• Angoulvant, Adela
• Agnamey, Patrice
• bonhomme, Julie
• Degeilh, Brigitte
• Chemla, Cathy
• Garnaud, Cécile
• Lollivier, Coralie
• angebault, Cécile
• Delaunay, Pascal
• Desoubeaux, Guillaume
• Fréalle, Emilie
• Grenouillet, Frédéric
• Morio, Florent
• Botterel, Françoise
• Belkadi, Ghania
• Yera, Hélène
• Nevez, Gilles
• Iriart, Xavier
• Accoceberry, Isabelle
• Brunet, Julie
• Thellier, Marc
• Rabodonirina, Meja
• Sasso, Milene
• Miossec, Charline
• Nicolas, Murielle
• Desbois, Nicole
• Poirier, Philippe
• Pomares, Christelle
• Houze, Sandrine
• Le govic, Yohann
• Bellanger, Anne Pauline
• Labbe, Franck
• Darde, Marie Laure
• Duquesnoy, Olivier
• Flori, Pierre
• Bastien, Patrick
• Gueudet, Thomas
• Villena, Isabelle
• Aubert, Dominique
• Cateau, Estelle
• Bougnoux, Marie-Elisabeth
• Kapel, Nathalie
• Dannaoui, Eric
• Valentin, Alexis
• Totet, Anne
• Menotti, Jean
• Blanchet, Denis
• Demar, Magalie
• Dutoit, Emmanuel
• Piarroux, Renaud
• Sitterle, Emilie
• Magne, Denis
• Hamane, Samsa
• Berry, Antoine
• Ramade, Cecile
• Favennec, Loïc
• Dalle, Frédéric

Titel

Human cryptosporidiosis in immunodeficient patients in France (2015–2017)

Ist Teil von

• Experimental parasitology, 2018-09, Vol.192, p.108-112

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Cryptosporidiosis is a common disease in children and immunodeficient individuals. In 2006, a national network was set up on the surveillance of human cryptosporidiosis in France. Since January 2015, the 41 tertiary care hospitals and the 3 private laboratories of the French National Network on the surveillance of human cryptosporidiosis have been able to declare confirmed cases of cryptosporidiosis online. Between 2015 and 2017, 210 cases of cryptosporidiosis were declared in immunodeficient patients in France; Cryptosporidium parvum and Cryptosporidium hominis represented 66% and 22% of cases, respectively. A peak was observed in autumn. Cryptosporidiosis occurred mainly in a context of solid organ transplantation (SOT) (49%) and of HIV infection (30%). In SOT recipients, cryptosporidiosis appeared more frequently in the first 6 months post transplantation. Regarding cases declared in SOT recipients, mycophenolate mofetil was used in 68%. A mortality rate of 6% was observed. Present results underline the importance of screening for cryptosporidiosis in immunocompromised patients suffering from diarrhea, especially in the course of major cell mediated immunodeficiency or even systematic screening before SOT. Exclusive Cryptosporidium free water feeding could be suggested during major cell mediated immunodeficiency. [Display omitted] •Cryptosporidiosis is more frequent in SOT immunodeficient patients.•Intense immune cellular deficiency is implicated.•Waterborne infection is more likely.•Systematic cryptosporidiosis screening before SOT is suitable.