Details

Autor(en) / Beteiligte

• Fuhrmann, Marine
• Richard, Gaëlle
• Quéré, Claudie
• Petton, Bruno
• Pernet, Fabrice

Titel

Low pH reduced survival of the oyster Crassostrea gigas exposed to the Ostreid herpesvirus 1 by altering the metabolic response of the host

Ist Teil von

• Aquaculture, 2019-03, Vol.503, p.167-174

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2019

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Environmental change in the marine realm has been accompanied by emerging diseases as new pathogens evolve to take advantage of hosts weakened by environmental stress. Here we investigated how an exposure to reduced seawater pH influenced the response of the oyster Crassostrea gigas to an infection by the Ostreid herpesvirus type I (OsHV-1). Oysters were acclimated at pH 8.1 or pH 7.8 and then exposed to OsHV-1. Their survival was monitored and oyster tissues were sampled for biochemical analyses. The survival of oysters exposed to OsHV-1 at pH 7.8 was lower (33.5%) than that of their counterparts at pH 8.1 (44.8%) whereas levels of OsHV-1 DNA were similar. Energetic reserves, fatty acid composition and prostaglandin levels in oyster did not vary consistently with pH, infection or their interactions. However, there was a reduction in the activities of superoxide dismutase (SOD) and nitric oxide synthase (iNOS) in oysters at low pH, which is associated with the observed difference in survival. •The susceptibility of Crassostrea gigas to OsHV-1 increased at pH 7.8 in comparison to pH 8.1•The amount of OsHV-1 in oyster tissues was the same at both pH, suggesting the role of host metabolic response in differential survival•A lower activity of SOD and a basal activity of iNOS at pH 7.8, in comparison to pH 8.1, may have impaired the defence of oysters to OsHV-1 explaining the lower survival