Details

Autor(en) / Beteiligte

• Villain, Adrien
• Gallot-Lavallée, Lucie
• Blanc, Guillaume
• Maumus, Florian

Titel

Giant viruses at the core of microscopic wars with global impacts

Ist Teil von

• Current opinion in virology, 2016-04, Vol.17, p.130-137

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• •NCLDVs are important parasites of unicellular eukaryotic plankton.•Virophages and transpovirons are themselves parasites of NCLDVs.•Virophages have evolved different modes on infection.•Competition fosters emergence of novel molecular defence mechanisms.•Marine virophages and transpovirons influence the global impact of NCLDVs. The unicellular eukaryotes (also called protists) that inhabit the contemporary oceans have large impacts on major biogeochemical cycles. Populations of oceanic protists are to a large extent regulated by their viral parasites, especially nucleocytoplasmic large DNA viruses (NCLDVs). NCLDVs can themselves be the prey of smaller viruses called virophages and can also be infected by transposable elements termed transpovirons. These entangled parasitisms have fostered the emergence of sophisticated infection and defence strategies. In addition persistent contact has facilitated the exchange of genes between different parties. Recent advances shed light on the strategies that govern such microbial wars. Endogenous virophage-like elements found in the genome of a marine alga could for instance provide the host acquired immunity against NCLDVs. In return, it was recently speculated that virophage sequences can be hijacked by NCLDVs and used as genetic weapons against virophages.