Details

Autor(en) / Beteiligte

• Saintenac, Cyrille
• Lee, Wing-Sham
• Cambon, Florence
• Rudd, Jason J.
• King, Robert C.
• Marande, William
• Powers, Stephen J.
• Bergès, Hélène
• Phillips, Andy L.
• Uauy, Cristobal
• Hammond-Kosack, Kim E.
• Langin, Thierry
• Kanyuka, Kostya

Titel

Wheat receptor-kinase-like protein Stb6 controls gene-for-gene resistance to fungal pathogen Zymoseptoria tritici

Ist Teil von

• Nature genetics, 2018-03, Vol.50 (3), p.368-374

Ort / Verlag

New York: Nature Publishing Group US

Erscheinungsjahr

2018

Quelle

MEDLINE

Beschreibungen/Notizen

• Deployment of fast-evolving disease-resistance genes is one of the most successful strategies used by plants to fend off pathogens 1 , 2 . In gene-for-gene relationships, most cloned disease-resistance genes encode intracellular nucleotide-binding leucine-rich-repeat proteins (NLRs) recognizing pathogen-secreted isolate-specific avirulence (Avr) effectors delivered to the host cytoplasm 3 , 4 . This process often triggers a localized hypersensitive response, which halts further disease development 5 . Here we report the map-based cloning of the wheat Stb6 gene and demonstrate that it encodes a conserved wall-associated receptor kinase (WAK)-like protein, which detects the presence of a matching apoplastic effector 6 – 8 and confers pathogen resistance without a hypersensitive response 9 . This report demonstrates gene-for-gene disease resistance controlled by this class of proteins in plants. Moreover, Stb6 is, to our knowledge, the first cloned gene specifying resistance to Zymoseptoria tritici , an important foliar fungal pathogen affecting wheat and causing economically damaging septoria tritici blotch (STB) disease 10 – 12 . The authors report map-based cloning of the wheat Stb6 gene, which encodes a conserved wall-associated receptor kinase (WAK)-like protein. Stb6 confers gene-for-gene disease resistance to fungal pathogen Zymoseptoria tritici by recognition of a matching pathogen effector.