Details

Autor(en) / Beteiligte

• Popp, John
• Caminade, Anne‐Marie
• Hey‐Hawkins, Evamarie

Titel

Redox‐Switchable Transfer Hydrogenations with P‐Chiral Dendritic Ferrocenyl Phosphine Complexes

Ist Teil von

• European journal of inorganic chemistry, 2020-05, Vol.2020 (17), p.1654-1669

Ort / Verlag

Weinheim: Wiley Subscription Services, Inc

Erscheinungsjahr

2020

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Attaining absolute control over a catalytic process and, therewith, exploiting its full potential pleases scientists in their ambitious and ongoing endeavor to perform catalysis like Nature does. In this regard, redox‐switchable catalysis certainly holds great potential, constantly gaining importance in modern catalysis research. Herein, we report the application of P‐stereogenic dendritic ferrocenyl phosphines in the ruthenium‐catalyzed redox‐switchable transfer hydrogenation of a ketone yielding an enantioenriched alcohol. By adding a chemical oxidant or reductant, the catalytic activity of the complexes was reversibly switched off and back on again over the course of the hydrogen transfer reaction. This has been rationalized mainly in terms of a distinct electronic communication between the redox‐active group and the catalytic center. The highly functionalized dendritic catalysts presented here might impact the way prospective homogeneous catalysts will be designed. Will the fish reach the other side? Or will the redox‐switchable cat catch a delicious treat? A single electron determines the fate of the fish. Depending on the redox state, the cat will let the fish pass to perform the hydrogen transfer to the product bowl (reduced state) or it will use its sharp claws to frighten them to remain in the substrate bowl (oxidized state).