Details

Autor(en) / Beteiligte

• Frat, Jean-Pierre
• Thille, Arnaud W
• Mercat, Alain
• Girault, Christophe
• Ragot, Stéphanie
• Perbet, Sébastien
• Prat, Gwénael
• Boulain, Thierry
• Morawiec, Elise
• Cottereau, Alice
• Devaquet, Jérôme
• Nseir, Saad
• Razazi, Keyvan
• Mira, Jean-Paul
• Argaud, Laurent
• Chakarian, Jean-Charles
• Ricard, Jean-Damien
• Wittebole, Xavier
• Chevalier, Stéphanie
• Herbland, Alexandre
• Fartoukh, Muriel
• Constantin, Jean-Michel
• Tonnelier, Jean-Marie
• Pierrot, Marc
• Mathonnet, Armelle
• Béduneau, Gaëtan
• Delétage-Métreau, Céline
• Richard, Jean-Christophe M
• Brochard, Laurent
• Robert, René

Titel

High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure

Ist Teil von

• The New England journal of medicine, 2015-06, Vol.372 (23), p.2185-2196

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• Patients with acute hypoxemic respiratory failure were assigned to standard oxygen therapy, high-flow oxygen therapy, or noninvasive ventilation. The intubation rate did not differ significantly among the groups, but 90-day mortality was lower in the high-flow–oxygen group. Noninvasive positive-pressure ventilation (hereafter, noninvasive ventilation) reduces the need for endotracheal intubation and mortality among patients with acute exacerbations of chronic obstructive pulmonary disease 1 – 3 or severe cardiogenic pulmonary edema. 4 The physiological effects of noninvasive ventilation include a decrease in the work of breathing and improvement in gas exchange. In patients with acute hypoxemic respiratory failure, the need for mechanical ventilation is associated with high mortality, 5 but data on the overall effects of noninvasive ventilation with respect to the prevention of intubation and improvement in outcome are conflicting. 6 – 10 Previous studies have often included a heterogeneous population of patients with . . .