Details

Autor(en) / Beteiligte

• Harbaoui, Brahim, MD
• Courand, Pierre-Yves, MD
• Charles, Paul, MD
• Dauphin, Raphael, MD
• Boussel, Loic, MD, PhD
• Jegaden, Olivier, MD, PhD
• Dubreuil, Olivier, MD
• de Gevigney, Guy, MD, PhD
• Lantelme, Pierre, MD, PhD

Titel

Aortic Calcifications Present the Next Challenge After TAVR

Ist Teil von

• Journal of the American College of Cardiology, 2015-03, Vol.65 (10), p.1058-1060

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2015

Quelle

ScienceDirect

Beschreibungen/Notizen

• Transcatheter aortic valve replacement (TAVR) has now become a safe and effective alternative to surgery in patients with a contraindication or at high risk (2). Because patients considered for TAVR are elderly, implying that they often have a markedly remodeled aorta, the arterial component of the LV load is likely to be sizable; yet, the precise impact of aortic remodeling on cardiac outcomes after TAVR has never been tackled. In a first multivariable Cox regression model adjusted for arterial approach, peripheral artery disease, and previous coronary artery bypass grafting (or prevalence of coronary artery disease), AAC remained predictive of the outcome (tertiles 3 and 2 vs. 1 HR: 2.50; 95% CI: 1.23 to 5.09; p = 0.001; +1 Log increment of ACC HR: 1.70; 95% CI: 1.10 to 2.61; p = 0.016).