Lung cancer (Amsterdam, Netherlands), 2017-07, Vol.109, p.92-100
2017
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Details
- Autor(en) / Beteiligte
- Titel
- Lepidic predominant adenocarcinoma and invasive mucinous adenocarcinoma of the lung exhibit specific mucin expression in relation with oncogenic drivers
- Ist Teil von
- Lung cancer (Amsterdam, Netherlands), 2017-07, Vol.109, p.92-100
- Ort / Verlag
- Ireland: Elsevier B.V
- Erscheinungsjahr
- 2017
- Quelle
- Access via ScienceDirect (Elsevier)
- Beschreibungen/Notizen
- Highlights • The role of mucins expression in lepidic adenocarcinoma is not fully understood. • MUC1 is associated with lepidic predominant adenocarcinoma. • MUC5B, MUC5AC, and MUC6 are associated with invasive mucinous adenocarcinoma. • EGFR - and KRAS -driven tumors display specific mucins expression. • Oncogenic events may play a role in mucins expression in lepidic adenocarcinoma.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0169-5002eISSN: 1872-8332DOI: 10.1016/j.lungcan.2017.05.007Titel-ID: cdi_hal_primary_oai_HAL_hal_01535623v1
- Format
- –
- Schlagworte
- Adenocarcinoma, Mucinous - genetics, Adenocarcinoma, Mucinous - metabolism, Aged, Biomarkers, Tumor - genetics, Cancer, Carcinogenesis - genetics, DNA-Binding Proteins - metabolism, EGFR, Epithelium - physiology, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Genes, erbB-1 - genetics, Hematology, Oncology and Palliative Medicine, Hepatocyte Nuclear Factor 4 - metabolism, Human health and pathology, Humans, Invasive mucinous adenocarcinoma, KRAS, Lepidic predominant adenocarcinoma, Life Sciences, Lung Neoplasms - genetics, Lung Neoplasms - metabolism, Male, Mucin, Mucins - genetics, Mucins - metabolism, Oncogenes - genetics, Proto-Oncogene Proteins p21(ras) - genetics, Pulmonary Alveoli - pathology, Pulmonary/Respiratory, Pulmonology and respiratory tract, Transcription Factors - metabolism, Up-Regulation