Details

Autor(en) / Beteiligte

• Adali-Kaya, Zeynep
• Tse Sum Bui, Bernadette
• Falcimaigne-Cordin, Aude
• Haupt, Karsten

Titel

Molecularly Imprinted Polymer Nanomaterials and Nanocomposites: Atom-Transfer Radical Polymerization with Acidic Monomers

Ist Teil von

• Angewandte Chemie International Edition, 2015-04, Vol.54 (17), p.5192-5195

Auflage

International ed. in English

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2015

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Molecularly imprinted polymers (MIPs) are artificial receptors which can be tailored to bind target molecules specifically. A new method, using photoinitiated atom‐transfer radical polymerization (ATRP) for their synthesis as monoliths, thin films and nanoparticles is described. The synthesis takes place at room temperature and is compatible with acidic monomers, two major limitations for the use of ATRP with MIPs. The method has been validated with MIPs specific for the drugs testosterone and S‐propranolol. This study considerably widens the range of functional monomers and thus molecular templates which can be used when MIPs are synthesized by ATRP, as well as the range of physical forms of these antibody mimics, in particular films and lithographic patterns, and their post‐functionalization from living chain‐ends. Read the small (im)print: Molecularly imprinted polymers (MIPs) are artificial receptors which can be tailored to bind target molecules specifically. The title reaction is compatible with acidic monomers, for their synthesis as monoliths, thin films and nanoparticles. This paves the way for surface modification and lithographic patterning of MIPs and their postfunctionalization from living chain‐ends. ppy=2‐phenylpyridine.