FEBS letters, 2008-06, Vol.582 (13), p.1783-1787
2008
Details
- Autor(en) / Beteiligte
- Titel
- The antioxidant properties of serum albumin
- Ist Teil von
- FEBS letters, 2008-06, Vol.582 (13), p.1783-1787
- Ort / Verlag
- England: Elsevier B.V
- Erscheinungsjahr
- 2008
- Link zum Volltext
- Quelle
- Wiley Online Library - AutoHoldings Journals
- Beschreibungen/Notizen
- Free radicals are a normal component of cellular oxygen metabolism in mammals. However, free radical-associated damage is an important factor in many pathological processes. Glycation and oxidative damage cause protein modifications, frequently observed in numerous diseases. Albumin represents a very abundant and important circulating antioxidant. This review brings together recent insights on albumin antioxidant properties. First, it focuses on the different activities of albumin concerning protein antioxidation. In particular, we describe the role of albumin in ligand binding and free radical-trapping activities. In addition, physiological and pathological situations that modify the antioxidant properties of albumin are reported.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0014-5793eISSN: 1873-3468DOI: 10.1016/j.febslet.2008.04.057Titel-ID: cdi_hal_primary_oai_HAL_hal_01198355v1
- Format
- –
- Schlagworte
- acute respiratory distress syndrome, advanced glycation end products, AGE, Antioxidant, ARDS, CML, Free Radical Scavengers - chemistry, Free Radical Scavengers - metabolism, Free Radicals - metabolism, H2O2, HSA, Human health and pathology, human serum albumin, Humans, hydrogen peroxide, LCFA, LDL, Life Sciences, Ligands, long-chain fatty acids, low-density lipoprotein, N(epsilon)-(carboxymethyl)lysine, nitric oxide, Oxidation, Oxidation-Reduction, Oxidative stress, RAGE, reactive nitrogen species, reactive oxygen species, receptor for advanced glycation end products, RNS, ROS, Serum albumin, Serum Albumin - chemistry, Serum Albumin - metabolism