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Registry of Transcatheter Aortic-Valve Implantation in High-Risk Patients
Ist Teil von
The New England journal of medicine, 2012-05, Vol.366 (18), p.1705-1715
Ort / Verlag
Waltham, MA: Massachusetts Medical Society
Erscheinungsjahr
2012
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Data from a French registry of nearly 3200 transcatheter aortic-valve implantation (TAVI) procedures complement data from randomized clinical trials. This emerging technique shows promise in the treatment of high-risk patients with aortic stenosis.
Aortic stenosis is now the most frequently diagnosed valvular disease.
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,
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Surgical aortic-valve replacement is the definitive therapy for patients with severe symptomatic aortic stenosis.
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,
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Operative mortality is low among selected elderly patients but increases with the number and severity of coexisting illnesses.
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–
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A survey of hospitalized patients revealed the underreferral to surgery of those with severe symptomatic aortic stenosis.
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Transcatheter aortic-valve implantation (TAVI) was developed as an alternative to surgical aortic-valve replacement in this high-risk patient population. Ten years after the first implantation by Cribier and colleagues,
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more than 50,000 patients have been treated by TAVI worldwide. . . .