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Details

Autor(en) / Beteiligte
Titel
Registry of Transcatheter Aortic-Valve Implantation in High-Risk Patients
Ist Teil von
  • The New England journal of medicine, 2012-05, Vol.366 (18), p.1705-1715
Ort / Verlag
Waltham, MA: Massachusetts Medical Society
Erscheinungsjahr
2012
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
  • Data from a French registry of nearly 3200 transcatheter aortic-valve implantation (TAVI) procedures complement data from randomized clinical trials. This emerging technique shows promise in the treatment of high-risk patients with aortic stenosis. Aortic stenosis is now the most frequently diagnosed valvular disease. 1 , 2 Surgical aortic-valve replacement is the definitive therapy for patients with severe symptomatic aortic stenosis. 2 , 3 Operative mortality is low among selected elderly patients but increases with the number and severity of coexisting illnesses. 4 – 6 A survey of hospitalized patients revealed the underreferral to surgery of those with severe symptomatic aortic stenosis. 7 Transcatheter aortic-valve implantation (TAVI) was developed as an alternative to surgical aortic-valve replacement in this high-risk patient population. Ten years after the first implantation by Cribier and colleagues, 8 more than 50,000 patients have been treated by TAVI worldwide. . . .

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