Details

Autor(en) / Beteiligte

• Simon, Marc-Olivier
• Martinez, Rémi
• Genêt, Jean-Pierre
• Darses, Sylvain

Titel

Ruthenium-Catalyzed CH Bond Activation of Michael Acceptors: An Unusual Reactivity Leading to Allylsilanes

Ist Teil von

• Advanced synthesis & catalysis, 2009-01, Vol.351 (1-2), p.153-157

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2009

Quelle

Wiley Online Library - AutoHoldings Journals

Beschreibungen/Notizen

• We report here an improved catalyst for the functionalization of Michael acceptors, involving CC bond formation via CH bond activation, using an in situ generated ruthenium active species. Moreover, on some particular substrates, the CH functionalization resulted unexpectedly in the formation of allylsilanes rather than in the expected conjugated adducts, affording a new straightforward methodology to access useful stereodefined trisubstituted allylsilanes via CH bond activation. Preliminary results have shown that they were reactive in the allylation of aldehydes, providing an access to alcohols bearing a quaternary carbon center.