The Journal of infectious diseases, 2009-02, Vol.199 (4), p.561-564
2009
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Details
- Autor(en) / Beteiligte
- Titel
- New strain of Human T Lymphotropic Virus (HTLV) type 3 in a Pygmy from Cameroon with peculiar HTLV serologic results
- Ist Teil von
- The Journal of infectious diseases, 2009-02, Vol.199 (4), p.561-564
- Ort / Verlag
- Oxford: The University of Chicago Press
- Erscheinungsjahr
- 2009
- Quelle
- Oxford Journals 2020 Medicine
- Beschreibungen/Notizen
- A search for human T lymphotropic virus (HTLV) types 1 and 2 and related viruses was performed by serological and molecular means on samples obtained from 421 adult villagers from the southern Cameroon forest areas. One individual (a 56- year-old Baka Pygmy hunter) was found to be HTLV-3 infected; however, there was a low proviral load in blood cells. Complete sequence analysis of this virus (HTLV-3Lobak18) indicated a close relationship to human HTLV-3Pyl43 and simian STLV-3CTO604 strains. Plasma samples from Lobak18, the HTLV-3 infected individual, exhibited a peculiar “HTLV- 2-like” pattern on Western blot analysis and were serologically untypeable by line immunoassay. These results were different from those for the 2 previously reported HTLV-3 strains, raising questions about serological confirmation of infection with such retroviruses.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0022-1899eISSN: 1537-6613DOI: 10.1086/596206Titel-ID: cdi_hal_primary_oai_HAL_hal_00358082v1
- Format
- –
- Schlagworte
- Adult, Biological and medical sciences, Blood plasma, Blotting, Western, Cameroon, Deltaretrovirus, Deltaretrovirus - classification, Deltaretrovirus - genetics, Deltaretrovirus - immunology, Deltaretrovirus - isolation & purification, Deltaretrovirus Infections, Deltaretrovirus Infections - blood, Deltaretrovirus Infections - virology, Ethnic Groups, Female, Fundamental and applied biological sciences. Psychology, HTLV-I Infections, HTLV-I Infections - virology, HTLV-II Infections, HTLV-II Infections - virology, Human T lymphotropic virus 1, Human T lymphotropic virus 2, Human T lymphotropic virus 3, Human T-lymphotropic virus, Human T-lymphotropic virus 1 - genetics, Human T-lymphotropic virus 2 - genetics, Humans, Immunoassay, Infectious diseases, Life Sciences, Male, Medical sciences, Microbiology, Microbiology and Parasitology, Middle Aged, Miscellaneous, Phylogeny, Polymerase Chain Reaction, Primates, Reactivity, Retroviridae Proteins, Retroviridae Proteins - blood, Retroviridae Proteins - genetics, Retrovirus, Simian T lymphotropic virus 3, T lymphocytes, Viral Load, Viremia, Virology, Viruses