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Invariant Natural Killer T Cells in Bronchial Asthma
Ist Teil von
The New England journal of medicine, 2006-06, Vol.354 (24), p.2613-2616
Ort / Verlag
United States: Massachusetts Medical Society
Erscheinungsjahr
2006
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
To the Editor:
We have not found a remarkably high proportion of CD1d-restricted natural killer T cells (>60 percent of CD3+ cells) in bronchoalveolar-lavage specimens from patients with allergic asthma, as reported by Akbari et al. (March 16 issue).
1
In five patients with allergic asthma, we found that only 0.4 to 2.1 percent of lymphocytes in bronchoalveolar-lavage fluid were natural killer T cells, on the basis of costaining with 6B11 and Vα24 antibodies (see Figure 1 of the Supplementary Appendix, available with the full text of this letter at www.nejm.org). We believe this discrepancy may result from fact that the authors . . .