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Feline rabies caused by a viral variant of insectivorous bat/Raiva felina por variante virai de morcegos insetivoros
Ist Teil von
Ciência rural, 2024-10, Vol.54 (10), p.1
Ort / Verlag
Universidade Federal de Santa Maria
Erscheinungsjahr
2024
Quelle
Free E-Journal (出版社公開部分のみ)
Beschreibungen/Notizen
Rabies is an invariably fatal infectious-contagious viral disease caused by viruses in the genus Lyssavirus, which affects the central nervous system of domestic and wild mammals. This study draw attention to the importance of insectivorous bats and domestic cats in the epidemiology of rabies. For this, two cases of rabies registered in domestic cats in the southeast region of Rio Grande do Sul were analyzed. Diagnoses were based on histological alterations and positive staining for the virus in direct immunofluorescence with confirmation by biological test, immunohistochemical evaluation and identification of the rabies virus variant by polymerase chain reaction. In Brazil, a change in the epidemiological profile of rabies has been observed, in which bats play a major role in the current chain of transmission of the disease. It is noteworthy, that the antigenic viral variant AgV-4, typical of the insectivorous bat Tadarida brasiliensis, was identified in the domestic cats affected in this study. Key words: feline rabies, Tadarida brasiliensis, domestic cat, Agv-4 variant, insectivorous bat. A raiva e uma enfermidade virai infectocontagiosa, invariavelmente fatal, causada por Lyssavirus, que afeta o sistema nervoso central de mamiferos domesticos e silvestres. O objetivo deste estudo foi alertar para a importancia de morcegos insetivoros e dos felinos domesticos na epidemiologia da raiva. Para isso, foram analisados dois casos de raiva registrados em gatos domesticos na regiao sudeste do Rio Grande do Sul. Os diagnosticos basearam-se nas alteracoes histologicas e na marcacao positiva para o virus na imunofluorescencia direta com confirmacao por prova biologica, avaliacao imuno-histoquimica e identificacao da variante do virus rabico por reacao de polimerase em cadeia. No Brasil tem sido observado uma mudanca no perfil epidemiologico da raiva, no qual os morcegos assumem papel principal na cadeia atual de transmissao da doenca.Chama-se a atencao que a variante virai antigenica AgV-4, propria do morcego insetivoro Tadarida brasiliensis, foi identificada nos felinos domesticos afetados neste estudo. Palavras-chave: raiva felina, Tadarida brasiliensis. gato domestico, variante AgV-4, morcego insetivoro.
Sprache
Englisch
Identifikatoren
ISSN: 0103-8478
eISSN: 1678-4596
DOI: 10.1590/0103-8478cr20230353
Titel-ID: cdi_gale_infotracmisc_A799981072
Format
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