Details

Autor(en) / Beteiligte

• Özkan, Serhat
• Erer, Sevda
• Elibol, Bülent
• Özkaynak, Sehür Sibel
• Çakmur, Raif
• Akbostanci, Muhittin Cenk
• Hanagasi, Hasmet
• Dogu, Okan

Titel

Apomorphine in the Treatment of Parkinson's Disease/Parkinson Hastaligi Tedavisinde Apomorfin

Ist Teil von

• Türk nöroloji dergisi, 2021-12, Vol.27 (4), p.358

Ort / Verlag

Galenos Yayinevi Tic. Ltd

Erscheinungsjahr

2021

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Apomorphine is a dopamine agonist used in the treatment of some motor and non-motor complications during Parkinson's disease, which could be administered as an intermittent or continuous infusion. Although apomorphine treatment has been shown to be effective on motor fluctuations and dyskinesias, there is no sufficient consensus regarding the administration of apomorphine test or infusion, and the management of the treatment. In this review, our aim is to create a "treatment management guideline," which includes recommendations for the use of apomorphine in the clinical practice, and to discuss the problems encountered in both intermittent and continuous infusion applications, in the light of the literature. Keywords: Apomorphine, Parkinson's disease, treatment Apomorfin, Parkinson hastaligi seyrinde görülen bazi motor ve non-motor komplikasyonlarin tedavisinde kullanilan, intermitan ya da sürekli infüzyon seklinde uygulanabilen bir dopamin agonistidir. Apomorfin tedavisinin, motor dalgalanmalar ve diskineziler üzerine etkisi gösterilmis olmasina ragmen, apomorfin testi ya da infüzyon uygulamalari ve tedavinin yönetimi ile ilgili yeterli fikir birligi yoktur. Bu derlemede amacimiz, klinik pratikte apomorfinin kullanimi ile ilgili önerilerin yer aldigi "tedavi yönetim rehberi" olusturmak ve gerek intermitan gerekse de sürekli infüzyon uygulamalarinda karsilasilan sorunlari literatür bilgileri esliginde tartismaktir. Anahtar Kelimeler: Apomorfin, Parkinson hastaligi, tedavi