Details

Autor(en) / Beteiligte

• Garcia-Ulloa, Ana Cristina
• Landa-Anell, Victoria
• Melgarejo-Hernandez, Marco
• Villegas-Narvaez, Andrea
• Urbina-Arronte, Luz Elena
• Hernandez-Jimenez, Sergio

Titel

Assessment of a Multidisciplinary Intervention in Patients With BMI [greater than or equal to]35 kg/[m.sup.2] and Recently Diagnosed Type 2 Diabetes

Ist Teil von

• The journal of clinical endocrinology and metabolism, 2019-07, Vol.104 (7), p.2994

Ort / Verlag

Oxford University Press

Erscheinungsjahr

2019

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Context: Patients with a body mass index (BMI) [greater than or equal to]35 kg/[m.sup.2] have lower benefits with intensive treatments and metabolic control goals are more difficult to reach. Objective: Evaluate the effect of a comprehensive care program in patients with a BMI [greater than or equal to]35 kg/[m.sup.2]. Design: Prospective cohort study. Setting: Comprehensive Care Center in a National Institute of Health. Patients: Patients with type 2 diabetes, [less than or equal to]5 years of diagnosis, without disabling complications, nonsmokers, and a BMI <45 kg/[m.sup.2]. Interventions: Exercise and nutritional interventions are modified for patients with a higher BMI to achieve metabolic control. Main Outcome Measures: Main outcome is achievement of treatment goals defined as HbA1c <7%, low-density lipoprotein cholesterol (LDL-c) <100 mg/dL, and blood pressure <130/80 mm Hg. Secondary measures were the percentage of patients achieving three metabolic goals. Results: A total of 587 patients with annual evaluation were included. Mean age was 55.3 [+ or -] 9.5 years, 56.6% women, time since diagnosis of 1 year (0 to 5). BMI <35 kg/[m.sup.2] group included 521 patients and BMI [greater than or equal to]35 kg/[m.sup.2] group included 66 patients. In the BMI [greater than or equal to]35 kg/[m.sup.2] group, we observed a greater decrease in weight and fat mass at 3 months compared with <35 kg/[m.sup.2] group, but the HbA1c, LDL-c, or blood pressure goals were similar at 3 months and 1 year between groups. Conclusions: Comprehensive interventions are equally effective in patients with recently diagnosed type 2 diabetes with BMI [greater than or equal to]35 kg/[m.sup.2] compared with patients with a lower BMI. (J Clin Endocrinol Metab 104: 2994-3002, 2019)