Details

Autor(en) / Beteiligte

• Cohn, Stanton H
• Vartsky, David
• Vaswani, Ashok N
• Sawitsky, Arthur
• Rai, Kanti
• Gartenhaus, Willa
• Yasumura, Seiichi
• Ellis, Kenneth J

Titel

Changes in body composition of cancer patients following combined nutritional support

Ist Teil von

• Nutrition and cancer, 1982, Vol.4 (2), p.107-119

Ort / Verlag

United States: Taylor & Francis Group

Erscheinungsjahr

1982

Quelle

MEDLINE

Beschreibungen/Notizen

• Extract: The effects of combined nutritional support (parenteral, enteral, and oral) were measured in cancer patients unable to maintain normal alimentation. Changes in body composition were quantified by measurement of total body levels of nitrogen, potassium, water, and fat. The protein-calorie intake of the patients also was evaluated by dietary survey (4-day recall). Standard anthropometric and biochemical measurements for nutritional assessment were obtained for comparison. The dietary evaluation indicated that the dietary supplementation for all patients was more than adequate to meet their energy requirements. Almost all patients gained weight on the combined nutritional support regimens. Determination of body composition indicated that change in body weight was equal to the sum of the changes in body protein, total body water, and total body fat. Anthropometric data were consistent with the results of the body composition study. Information on the nature of the tissue gained, was obtained by comparison of body composition data with the ratio of protein:water:lean body mass for normal tissue. The mean gain of protein in the cancer patients was quite small (0.3-0.6 kg); the main change in body weight appeared to be the result of gains in body water and body fat. The total body nitrogen to potassium ratio served to define the extent of the tissue anabolism following hyperalimentation; the ratio dropped in the cancer patients following hyperalimentation, toward the value of the control subjects on ad libidum diets. The body compartment techniques described have demonstrated their usefulness in determining the effects of hyperalimentation on cancer patients. (author/wz)