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The effect of acute administration on the mycotoxin zearalenone to female pigs [Feed contaminant from moldy corn]
Ist Teil von
Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes, 1981, Vol.16 (3), p.239-252
Ort / Verlag
England: Taylor & Francis Group
Erscheinungsjahr
1981
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Crystalline zearalenone was administered to young female pigs at dose levels of 0, 3.5, 7.5 and 11.5 mg zearalenone/kg body weight. All animals receiving the mycotoxin exhibited vulva vag-initis and had enlarged reproductive tracts, 1 week after dosing. Free zearalenone was found in the blood, feces and urine of dosed animals. The highest zearalenone level detected was 2.61 ng/ml from a pig that received the 7.5 mg/kg dose. After 24 hours, feces collected contained on average up to 308 ng zearalenone per g of dried feces. Zearalenone levels of up to 59 ng/ml, and a -zearalenol levels of up to 155 ng/ml urine were found. ß -zearalenol was also detected in the urine.