Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
The prevalence of diabetes and obesity is increasing globally, causing a serious threat to human health. Regarding starch blocking, the α-amylase inhibitor (α-AI) of white kidney bean (Phaseolus vulgaris L.) stands out as a naturally abundant active substance. It reduces food glycemic index (GI) by inhibiting mammalian α-amylase activity and has been proven to be effective in controlling metabolic diseases such as diabetes and hyperlipidemia.
This review focuses on the inhibition mechanism of white kidney bean α-AI, constructs an α-AI detection system in actual food, and analyzes the challenges of the application of the inhibitors in food, including the influence of thermal processing on the structure and functional properties of α-AI.
White kidney bean α-AI can be used as a supplement to lower the dietary GI. Adding α-AI during food thermal processing may contribute to the formation of disulfide bonds, thereby improving the inhibition activity of α-amylase. In addition, white kidney bean α-AI can also control body weight and regulate intestinal flora. This study provides theoretical and technical guidance for further utilization or development of commercial low GI food using white kidney bean α-AI.
•Inhibition mechanism and functional characteristics of α-AI are summarized.•A holistic framework of α-AI detection in practical food applications is proposed.•Discuss the structural and functional changes of α-AI during thermal processing.•The latest developments of α-AI in low glycemic index food are addressed.•Future challenges require clarifying inhibition effect in thermal food processing.