Details

Autor(en) / Beteiligte

• Li, Jia
• Xu, Wenli
• Zhang, Wenchao
• Liu, Dingjin
• Jiang, Shuyang
• Liu, Guohua
• Wang, Yong
• Sun, Haoran
• Xu, Wenping
• Jiang, Biao
• Yao, Jianhua

Titel

Applications of intelligent technology in the evaluation of mutagenicity

Ist Teil von

• Mutation research. Genetic toxicology and environmental mutagenesis, 2024-07, Vol.897, p.503785, Article 503785

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2024

Link zum Volltext

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Bioassays are widely used in assessment of mutagenicity. Alternative methods have also been developed, including “intelligent evaluation”, which depends on the quality of data, strategies, and techniques. CISOC-PSMT is an Ames test prediction system. The strategies and techniques for intelligent evaluation and four applications of CISOC-PSMT are presented; roles in pesticide management, environmental protection, drug discovery, and safety management of chemicals are introduced. •Data and algorithms are essential ingredients of predictive models.•Evaluation of results by intelligent technology can complement bioassay results.•Intelligent technology will play a significant role in development of toxicology.