Details

Autor(en) / Beteiligte

• Heidinger, Martin
• Loesch, Julie M.
• Levy, Jeremy
• Maggi, Nadia
• Eller, Ruth S.
• Schwab, Fabienne D.
• Kurzeder, Christian
• Weber, Walter P.

Titel

Association of relative resection volume with patient-reported outcomes applying different levels of oncoplastic breast conserving surgery – A retrospective cohort study

Ist Teil von

• European journal of surgical oncology, 2024-09, Vol.50 (9), p.108478, Article 108478

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2024

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The American Society of Breast Surgeons (ASBrS) recently classified oncoplastic breast conserving surgery (OBCS) into two levels. The association of resection ratio during OBCS with patient-reported outcomes (PRO) is unclear. Patients with stage 0-III breast cancer undergoing OBCS between 01/2011-04/2023 at a Swiss university hospital, who completed at least one postoperative BREAST-Q PRO questionnaire were identified from a prospectively maintained institutional database. Outcomes included differences in PROs between patients after ASBrS level I (<20 % of breast tissue removed) versus level II surgery (20–50 %). Of 202 eligible patients, 129 (63.9 %) underwent level I OBCS, and 73 (36.1 %) level II. Six patients (3.0 %) who underwent completion mastectomy were excluded. The median time to final PROs was 25.4 months. Patients undergoing ASBrS level II surgery were more frequently affected by delayed wound healing (p < 0.001). ASBrS level was not found to independently predict any BreastQ domain. However, delayed wound healing was shown to reduce short-term physical well-being (estimated difference −26.27, 95 % confidence interval [CI] −39.33 to −13.22, p < 0.001). Higher age was associated with improved PROs. ASBrS level II surgery allows the removal of larger tumors without impairing PROs. Preventive measures for delayed wound healing and close postoperative follow-up to promptly treat wound healing disorders may avoid short-term reductions in physical well-being. •High-volume oncoplastic breast conserving surgery allows removal of larger tumors.•High-volume oncoplastic surgery does not impair patient-reported outcomes.•Delayed wound healing impairs short-term physical well-being.