Details

Autor(en) / Beteiligte

• Nichols, W.W.
• Lardenoije, R.
• Ledwith, B.J.
• Brouwer, K.
• Manam, S.
• Vogels, R.
• Kaslow, D.
• Zuidgeest, D.
• Bett, A.J.
• Chen, L.
• van der Kaaden, M.
• Galloway, S.M.
• Hill, R.B.
• Machotka, S.V.
• Anderson, C.A.
• Lewis, J.
• Martinez, D.
• Lebron, J.
• Russo, C.
• Valerio, D.
• Bout, A.

Titel

7 - Propagation of Adenoviral Vectors: Use of PER.C6™ Cells

Ist Teil von

• Adenoviral Vectors for Gene Therapy, 2016, p.163-196

Auflage

Second Edition

Ort / Verlag

Elsevier Inc

Erscheinungsjahr

2016

Link zum Volltext

Beschreibungen/Notizen

• Gene therapy aims at the introduction of gene(s) into somatic cells of humans for therapeutic purposes. The success of gene therapy is therefore dependent on the efficiency by which a therapeutic gene can be transferred to the patient's target tissues. In many cases, viruses are exploited for gene transfer purposes, and in particular gene transfer vectors derived from adenoviruses (adenoviral vectors) are often used to achieve this.