Details

Autor(en) / Beteiligte

• Audollent, R
• Eveno, C
• Dohan, A
• Sarda, L
• Jouvin, I
• Soyer, P
• Pocard, M

Titel

Pitfalls and mimickers on18 F-FDG-PET/CT in peritoneal carcinomatosis from colorectal cancer: An analysis from 37 patients

Ist Teil von

• Journal of visceral surgery, 2015, Vol.152 (5), p.285-291

Erscheinungsjahr

2015

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Summary Background Optimal selection is critical in patients with peritoneal carcinomatosis (PC) in whom curative cytoreductive surgery can be anticipated.18 F-FDG-PET/CT may result in false-positive findings that may eliminate patients for whom cytoreductive surgery would be beneficial. Objectives To determine the rate of false-positive findings on18 F-FDG-PET/CT and clarify their causes in patients with suspected PC from colorectal cancer. Methods A retrospective analysis of 37 patients with suspected PC from colorectal cancer who had18 F-FDG-PET/CT before cytoreductive surgery was performed to determine the rate and the causes of false-positive findings.18 F-FDG-PET/CT was considered falsely positive when no tumor was found at surgery, histopathological analysis and follow-up. Results False-positive findings were observed in four patients, yielding a 11% (95%CI: 3–25%) false-positive rate on a per-patient basis. The causes of false-positives were elucidated in two patients (surgical mesh after umbilical hernia repair and one foreign body granuloma). Conclusion False-positive findings on18 F-FDG-PET/CT are observed in 11% of patients with suspected PC from colorectal cancer. Familiarity with false-positive findings would result in more accurate selection of patients candidates to cytoreductive surgery.