Details

Autor(en) / Beteiligte

• Pastagia, Mina
• Kleinman, Lawrence C
• Lacerda de la Cruz, Eliesel G
• Jenkins, Stephen G

Titel

Predicting risk for death from MRSA bacteremia

Ist Teil von

• Emerging infectious diseases, 2012-07, Vol.18 (7), p.1072-1080

Ort / Verlag

United States: U.S. National Center for Infectious Diseases

Erscheinungsjahr

2012

Quelle

MEDLINE

Beschreibungen/Notizen

• Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is often fatal. To determine predictors of risk for death, we conducted a retrospective cohort study. We examined 699 episodes of MRSA bacteremia involving 603 patients admitted to an academic medical center in New York City during 2002-2007. Data came from chart reviews, hospital databases, and recultured frozen MRSA specimens. Among the 699 episodes, 55 were caused by vancomycin-intermediate resistant S. aureus strains, 55 by heteroresistant vancomycin-intermediate S. aureus strains, and 589 by non-vancomycin-resistant strains; 190 (31.5%) patients died. We used regression risk analysis to quantify the association between clinical correlates and death. We found that older age, residence in a nursing home, severe bacteremia, and organ impairment were independently associated with increased risk for death; consultation with an infectious disease specialist was associated with lower risk for death; and MRSA strain types were not associated with risk for death.