Details

Autor(en) / Beteiligte

• van Wijngaarden, Aniek L
• Kruithof, Boudewijn P T
• Vinella, Tommaso
• Barge-Schaapveld, Daniela Q C M
• Ajmone Marsan, Nina

Titel

Characterization of Degenerative Mitral Valve Disease: Differences between Fibroelastic Deficiency and Barlow's Disease

Ist Teil von

• Journal of cardiovascular development and disease, 2021-02, Vol.8 (2), p.23

Ort / Verlag

Switzerland: MDPI

Erscheinungsjahr

2021

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Degenerative mitral valve disease causing mitral valve prolapse is the most common cause of primary mitral regurgitation, with two distinct phenotypes generally recognized with some major differences, i.e., fibroelastic deficiency (FED) and Barlow's disease. The aim of this review was to describe the main histological, clinical and echocardiographic features of patients with FED and Barlow's disease, highlighting the differences in diagnosis, risk stratification and patient management, but also the still significant gaps in understanding the exact pathophysiology of these two phenotypes.