Life (Basel, Switzerland), 2024-04, Vol.14 (4), p.524
2024
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- Autor(en) / Beteiligte
- Titel
- Applied Cardio-Oncology in Hematological Malignancies: A Narrative Review
- Ist Teil von
- Life (Basel, Switzerland), 2024-04, Vol.14 (4), p.524
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2024
- Quelle
- EZB Electronic Journals Library
- Beschreibungen/Notizen
- Applied cardio-oncology in hematological malignancies refers to the integration of cardiovascular care and management for patients with blood cancer, particularly leukemia, lymphoma, and multiple myeloma. Hematological cancer therapy-related cardiotoxicity deals with the most common cardiovascular complications of conventional chemotherapy, targeted therapy, immunotherapy, chimeric antigen receptor T (CAR-T) cell and tumor-infiltrating lymphocyte therapies, bispecific antibodies, and hematopoietic stem cell transplantation. This narrative review focuses on hematological cancer-therapy-related cardiotoxicity's definition, risk stratification, multimodality imaging, and use of cardiac biomarkers to detect clinical and/or subclinical myocardial dysfunction and electrical instability. Moreover, the most common cardiotoxic profiles of the main drugs and/or therapeutic interventions in patients with hematological malignancies are described thoroughly.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2075-1729eISSN: 2075-1729DOI: 10.3390/life14040524Titel-ID: cdi_doaj_primary_oai_doaj_org_article_fb885b53cc5d48f0a430900011768674
- Format
- –
- Schlagworte
- Antibodies, Antigens, Antimitotic agents, Antineoplastic agents, Asymptomatic, Biomarkers, Bispecific antibodies, Blood cancer, Cancer, Cancer therapies, Cardiac arrhythmia, Cardiac function, cardio-oncology, Cardiomyocytes, Cardiotoxicity, Cardiovascular diseases, Care and treatment, Chemotherapy, Chimeric antigen receptors, Collaboration, Complications and side effects, Heart failure, hematological malignancies, Hematology, Hematopoietic stem cells, Hypertension, Immunosuppressive agents, Immunotherapy, Kinases, Leukemia, Lymphocytes, Lymphoma, Lymphomas, Malignancy, Metabolism, multimodality imaging, Multiple myeloma, myocardial dysfunction, Narratives, Oncology, Patients, Peptides, Radiation therapy, Risk factors, Stem cell transplantation, Stem cells, Stratification, Surveillance, Therapeutic applications, Toxicity, Transplantation