Details

Autor(en) / Beteiligte

• Ciocan-Cartita, Cristina Alexandra
• Jurj, Ancuța
• Buse, Mihail
• Gulei, Diana
• Braicu, Cornelia
• Raduly, Lajos
• Cojocneanu, Roxana
• Pruteanu, Lavinia Lorena
• Iuga, Cristina Adela
• Coza, Ovidiu
• Berindan-Neagoe, Ioana

Titel

The Relevance of Mass Spectrometry Analysis for Personalized Medicine through Its Successful Application in Cancer "Omics"

Ist Teil von

• International journal of molecular sciences, 2019-05, Vol.20 (10), p.2576

Ort / Verlag

Switzerland: MDPI AG

Erscheinungsjahr

2019

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Mass spectrometry (MS) is an essential analytical technology on which the emerging omics domains; such as genomics; transcriptomics; proteomics and metabolomics; are based. This quantifiable technique allows for the identification of thousands of proteins from cell culture; bodily fluids or tissue using either global or targeted strategies; or detection of biologically active metabolites in ultra amounts. The routine performance of MS technology in the oncological field provides a better understanding of human diseases in terms of pathophysiology; prevention; diagnosis and treatment; as well as development of new biomarkers; drugs targets and therapies. In this review; we argue that the recent; successful advances in MS technologies towards cancer omics studies provides a strong rationale for its implementation in biomedicine as a whole.