Details

Autor(en) / Beteiligte

• Kim, Myung-Shin
• Lozano, Roberto
• Kim, Ji Hong
• Bae, Dong Nyuk
• Kim, Sang-Tae
• Park, Jung-Ho
• Choi, Man Soo
• Kim, Jaehyun
• Ok, Hyun-Choong
• Park, Soo-Kwon
• Gore, Michael A
• Moon, Jung-Kyung
• Jeong, Soon-Chun

Titel

The patterns of deleterious mutations during the domestication of soybean

Ist Teil von

• Nature communications, 2021-01, Vol.12 (1), p.97-97, Article 97

Ort / Verlag

England: Nature Publishing Group

Erscheinungsjahr

2021

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• Globally, soybean is a major protein and oil crop. Enhancing our understanding of the soybean domestication and improvement process helps boost genomics-assisted breeding efforts. Here we present a genome-wide variation map of 10.6 million single-nucleotide polymorphisms and 1.4 million indels for 781 soybean individuals which includes 418 domesticated (Glycine max), 345 wild (Glycine soja), and 18 natural hybrid (G. max/G. soja) accessions. We describe the enhanced detection of 183 domestication-selective sweeps and the patterns of putative deleterious mutations during domestication and improvement. This predominantly selfing species shows 7.1% reduction of overall deleterious mutations in domesticated soybean relative to wild soybean and a further 1.4% reduction from landrace to improved accessions. The detected domestication-selective sweeps also show reduced levels of deleterious alleles. Importantly, genotype imputation with this resource increases the mapping resolution of genome-wide association studies for seed protein and oil traits in a soybean diversity panel.