Viruses, 2023-01, Vol.15 (2), p.359
2023
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Details
- Autor(en) / Beteiligte
- Titel
- Transmissible Gastroenteritis Virus: An Update Review and Perspective
- Ist Teil von
- Viruses, 2023-01, Vol.15 (2), p.359
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2023
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Transmissible gastroenteritis virus (TGEV) is a member of the alphacoronavirus genus, which has caused huge threats and losses to pig husbandry with a 100% mortality in infected piglets. TGEV is observed to be recombining and evolving unstoppably in recent years, with some of these recombinant strains spreading across species, which makes the detection and prevention of TGEV more complex. This paper reviews and discusses the basic biological properties of TGEV, factors affecting virulence, viral receptors, and the latest research advances in TGEV infection-induced apoptosis and autophagy to improve understanding of the current status of TGEV and related research processes. We also highlight a possible risk of TGEV being zoonotic, which could be evidenced by the detection of CCoV-HuPn-2018 in humans.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1999-4915eISSN: 1999-4915DOI: 10.3390/v15020359Titel-ID: cdi_doaj_primary_oai_doaj_org_article_ee45d549726b4dc98ea8311bccf3c70a
- Format
- –
- Schlagworte
- Alphacoronavirus, Animals, Apoptosis, Autophagy, Causes of, Complications and side effects, Coronavirus infections, Coronaviruses, Diarrhea, Disease transmission, Epidemics, Epidemiology, Gastroenteritis, Genetic aspects, Genomes, Hogs, Humans, Identification and classification, Infections, Phylogenetics, Pneumonia, Proteins, Public health, Receptor mechanisms, Receptors, Virus, Respiratory diseases, Review, Risk factors, Severe acute respiratory syndrome coronavirus 2, Swine, TGEV, TGEV variant strains, TGEV virulence, Transmissible gastroenteritis, Transmissible gastroenteritis virus, Viral infections, Virulence, Zoonoses, zoonotic