Vaccines (Basel), 2024-05, Vol.12 (5), p.483
2024
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Details
- Autor(en) / Beteiligte
- Titel
- Tuberculosis Vaccines and T Cell Immune Memory
- Ist Teil von
- Vaccines (Basel), 2024-05, Vol.12 (5), p.483
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2024
- Quelle
- EZB Electronic Journals Library
- Beschreibungen/Notizen
- Tuberculosis (TB) remains a major infectious disease partly due to the lack of an effective vaccine. Therefore, developing new and more effective TB vaccines is crucial for controlling TB. ( ) usually parasitizes in macrophages; therefore, cell-mediated immunity plays an important role. The maintenance of memory T cells following infection or vaccination is a hallmark of immune protection. This review analyzes the development of memory T cells during infection and vaccine immunization, especially on immune memory induced by BCG and subunit vaccines. Furthermore, the factors affecting the development of memory T cells are discussed in detail. The understanding of the development of memory T cells should contribute to designing more effective TB vaccines and optimizing vaccination strategies.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2076-393XeISSN: 2076-393XDOI: 10.3390/vaccines12050483Titel-ID: cdi_doaj_primary_oai_doaj_org_article_eaefd876b764441e9b7a52ca0d346b6b
- Format
- –
- Schlagworte
- Analysis, Antigens, Apoptosis, BCG, Cell-mediated immunity, Cells, Clinical trials, Dosage and administration, Evaluation, HIV, Human immunodeficiency virus, immune memory, Immunization, Immunologic memory, Immunological memory, Infections, Infectious diseases, Lymphocytes, Lymphocytes T, Macrophages, Memory cells, Metabolism, Pathogens, Physiological aspects, Public health, subunit vaccine, T cell, T cells, Tuberculosis, Tuberculosis vaccines, vaccine, Vaccines