International journal of molecular sciences, 2020-12, Vol.22 (1), p.205
2020
Details
- Autor(en) / Beteiligte
- Titel
- Novel Perspectives Regarding the Pathology, Inflammation, and Biomarkers of Acute Respiratory Distress Syndrome
- Ist Teil von
- International journal of molecular sciences, 2020-12, Vol.22 (1), p.205
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2020
- Link zum Volltext
- Quelle
- Electronic Journals Library
- Beschreibungen/Notizen
- Acute respiratory distress syndrome (ARDS) is an acute inflammation of the lung resulting from damage to the alveolar-capillary membrane, and it is diagnosed using a combination of clinical and physiological variables. ARDS develops in approximately 10% of hospitalised patients with pneumonia and has a mortality rate of approximately 40%. Recent research has identified several biomarkers associated with ARDS pathophysiology, and these may be useful for diagnosing and monitoring ARDS. They may also highlight potential therapeutic targets. This review summarises our current understanding of those clinical biomarkers: (1) biomarkers of alveolar and bronchiolar injury, (2) biomarkers of endothelial damage and coagulation, and (3) biomarkers for treatment responses.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1422-0067, 1661-6596eISSN: 1422-0067DOI: 10.3390/ijms22010205Titel-ID: cdi_doaj_primary_oai_doaj_org_article_e322ba8e069b4cbc89aa58cd0ea53e5e
- Format
- –
- Schlagworte
- acute respiratory distress syndrome, Alveoli, Biomarkers, Coagulation, Cytokines, Damage, Glycoproteins, Illnesses, Inflammation, Intensive care, Lung diseases, Medical prognosis, molecular pathway, Mortality, Permeability, Physiology, Plasma, Proteins, Respiratory distress syndrome, Review, Sepsis, Sleep apnea, Surfactants, Therapeutic targets, therapeutics, Trauma, Tumor necrosis factor-TNF, Ventilators