Details

Autor(en) / Beteiligte

• Gubbels, Jennifer Aa
• Claussen, Nick
• Kapur, Arvinder K
• Connor, Joseph P
• Patankar, Manish S

Titel

The detection, treatment, and biology of epithelial ovarian cancer

Ist Teil von

• Journal of ovarian research, 2010-03, Vol.3 (1), p.8-8, Article 8

Ort / Verlag

England: BioMed Central Ltd

Erscheinungsjahr

2010

Quelle

SpringerLink_现刊

Beschreibungen/Notizen

• Ovarian cancer is particularly insidious in nature. Its ability to go undetected until late stages coupled with its non-descript signs and symptoms make it the seventh leading cause of cancer related deaths in women. Additionally, the lack of sensitive diagnostic tools and resistance to widely accepted chemotherapy regimens make ovarian cancer devastating to patients and families and frustrating to medical practitioners and researchers. Here, we provide an in-depth review of the theories describing the origin of ovarian cancer, molecular factors that influence its growth and development, and standard methods for detection and treatment. Special emphasis is focused on interactions between ovarian tumors and the innate and adaptive immune system and attempts that are currently underway to devise novel immunotherapeutic approaches for the treatment of ovarian tumors.