Biomolecules (Basel, Switzerland), 2021-09, Vol.11 (10), p.1410
2021
Details
- Autor(en) / Beteiligte
- Titel
- Lipopolysaccharide of the Yersinia pseudotuberculosis Complex
- Ist Teil von
- Biomolecules (Basel, Switzerland), 2021-09, Vol.11 (10), p.1410
- Ort / Verlag
- Switzerland: MDPI AG
- Erscheinungsjahr
- 2021
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Lipopolysaccharide (LPS), localized in the outer leaflet of the outer membrane, serves as the major surface component of the Gram-negative bacterial cell envelope responsible for the activation of the host's innate immune system. Variations of the LPS structure utilized by Gram-negative bacteria promote survival by providing resistance to components of the innate immune system and preventing recognition by TLR4. This review summarizes studies of the biosynthesis of Yersinia pseudotuberculosis complex LPSs, and the roles of their structural components in molecular mechanisms of yersiniae pathogenesis and immunogenesis.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2218-273XeISSN: 2218-273XDOI: 10.3390/biom11101410Titel-ID: cdi_doaj_primary_oai_doaj_org_article_d7e76fba88884fcd81e1e441a35bd8b4
- Format
- –
- Schlagworte
- Antigens, Bacteria, core, Gram-negative bacteria, Host-Pathogen Interactions - genetics, Host-Pathogen Interactions - immunology, Humans, Immune system, Immunity, Innate - genetics, Innate immunity, lipid A, Lipid A - genetics, Lipid A - immunology, Lipids, lipopolysaccharide (LPS), Lipopolysaccharides, Lipopolysaccharides - chemistry, Lipopolysaccharides - genetics, Lipopolysaccharides - immunology, Molecular modelling, Molecular Structure, pathogenicity factor, Pseudotuberculosis, Review, Salmonella, Signal transduction, Structure-Activity Relationship, TLR4 protein, Toll-like receptors, Yersinia pestis, Yersinia pseudotuberculosis, Yersinia pseudotuberculosis - chemistry, Yersinia pseudotuberculosis - immunology, Yersinia pseudotuberculosis - pathogenicity