Emerging infectious diseases, 2019-07, Vol.25 (7), p.1261-1270
2019
Details
- Autor(en) / Beteiligte
- Titel
- Bacillus cereus-Attributable Primary Cutaneous Anthrax-Like Infection in Newborn Infants, India
- Ist Teil von
- Emerging infectious diseases, 2019-07, Vol.25 (7), p.1261-1270
- Ort / Verlag
- United States: U.S. National Center for Infectious Diseases
- Erscheinungsjahr
- 2019
- Link zum Volltext
- Quelle
- EZB Free E-Journals
- Beschreibungen/Notizen
- During March 13-June 23, 2018, anthrax-like cutaneous lesions attributed to the Bacillus cereus group of organisms developed in 12 newborns in India. We traced the source of infection to the healthcare kits used for newborn care. We used multilocus sequence typing to characterize the 19 selected strains from various sources in hospital settings, including the healthcare kits. This analysis revealed the existence of a genetically diverse population comprising mostly new sequence types. Phylogenetic analysis clustered most strains into the previously defined clade I, composed primarily of pathogenic bacilli. We suggest that the synergistic interaction of nonhemolytic enterotoxin and sphingomyelinase might have a role in the development of cutaneous lesions. The infection was controlled by removing the healthcare kits and by implementing an ideal housekeeping program. All the newborns recovered after treatment with ciprofloxacin and amikacin.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1080-6040eISSN: 1080-6059DOI: 10.3201/eid2507.181493Titel-ID: cdi_doaj_primary_oai_doaj_org_article_d667c436dd3d49779e50ee48db698572
- Format
- –
- Schlagworte
- Analysis, Anthrax, Anthrax - diagnosis, Antibacterial agents, Attributable Primary Cutaneous Anthrax-Like Infection in Newborn Infants, India, Bacillus cereus, Bacillus cereus - classification, Bacillus cereus - genetics, Bacterial Proteins - genetics, Cross Infection - diagnosis, Cross Infection - epidemiology, Cross Infection - microbiology, cutaneous, Diagnosis, Differential, Enterotoxins - genetics, Gram-Positive Bacterial Infections - diagnosis, Gram-Positive Bacterial Infections - epidemiology, Gram-Positive Bacterial Infections - microbiology, Humans, India - epidemiology, Infant, Infant, Newborn, infants, Infants (Newborn), Infection, Multilocus Sequence Typing, Newborn infants, nosocomial, Phylogeny, Public Health Surveillance, Skin Diseases, Bacterial - diagnosis, Skin Diseases, Bacterial - epidemiology, Skin Diseases, Bacterial - microbiology, toxins