Clinical ophthalmology (Auckland, N.Z.), 2022-09, Vol.16, p.3225-3246
2022
Details
- Autor(en) / Beteiligte
- Titel
- Late-Onset Retinal Degeneration: Clinical Perspectives
- Ist Teil von
- Clinical ophthalmology (Auckland, N.Z.), 2022-09, Vol.16, p.3225-3246
- Ort / Verlag
- Auckland: Dove Medical Press Limited
- Erscheinungsjahr
- 2022
- Link zum Volltext
- Quelle
- EZB Electronic Journals Library
- Beschreibungen/Notizen
- Late-onset retinal degeneration (L-ORD) is a type of retinal dystrophy marked by nyctalopia and subretinal pigment epithelium deposits, which eventually promote retinal atrophy with final visual compromise. L-ORD may also present with changes in the anterior segment, notably long anterior zonules and iris atrophy, distinguishing it from other inherited eye conditions. Although it can clinically simulate age-related macular degeneration, L-ORD has a different course of progression and prognosis, requiring adequate diagnosis for patient counseling. This review summarizes the main clinical, genetic, pathophysiological, diagnostic, and therapeutic aspects of L-ORD to help ophthalmologists identify and manage this rare ocular disease. Keywords: retinal dystrophy, retinal degeneration, macular dystrophy, late-onset retinal degeneration, C1QTNF5, CTRP5
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1177-5483, 1177-5467eISSN: 1177-5483DOI: 10.2147/OPTH.S362691Titel-ID: cdi_doaj_primary_oai_doaj_org_article_d5209b4ec6b24302b89a9302bad92dd3
- Format
- –
- Schlagworte
- Age, Atrophy, Development and progression, Disease, Eye diseases, Genetic counseling, Genotype & phenotype, Health aspects, Health counseling, Histopathology, Macular degeneration, Mutation, Ophthalmology, Patients, Physiological aspects, Prognosis, Retina, retinal dystrophy retinal degeneration macular dystrophy late-onset retinal degeneration c1qtnf5 ctrp5, Review, Womens health