Nature communications, 2019-06, Vol.10 (1), p.2562-12, Article 2562
2019
Details
- Autor(en) / Beteiligte
- Titel
- Variation of a major facilitator superfamily gene contributes to differential cadmium accumulation between rice subspecies
- Ist Teil von
- Nature communications, 2019-06, Vol.10 (1), p.2562-12, Article 2562
- Ort / Verlag
- England: Nature Publishing Group
- Erscheinungsjahr
- 2019
- Link zum Volltext
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- Cadmium (Cd) accumulation in rice grain poses a serious threat to human health. While several transport systems have been reported, the complicity of rice Cd transport and accumulation indicates the necessity of identifying additional genes, especially those that are responsible for Cd accumulation divergence between indica and japonica rice subspecies. Here, we show that a gene, OsCd1, belonging to the major facilitator superfamily is involved in root Cd uptake and contributes to grain accumulation in rice. Natural variation in OsCd1 with a missense mutation Val449Asp is responsible for the divergence of rice grain Cd accumulation between indica and japonica. Near-isogenic line tests confirm that the indica variety carrying the japonica allele OsCd1 can reduce the grain Cd accumulation. Thus, the japonica allele OsCd1 may be useful for reducing grain Cd accumulation of indica rice cultivars through breeding.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2041-1723eISSN: 2041-1723DOI: 10.1038/s41467-019-10544-yTitel-ID: cdi_doaj_primary_oai_doaj_org_article_d369edf549334368b615429d68d46c0d
- Format
- –
- Schlagworte
- Accumulation, Alleles, Asparagine - genetics, Breeding, Cadmium, Cadmium - analysis, Cadmium - metabolism, Cell Membrane - metabolism, Chromosomes, CRISPR, Cultivars, Divergence, Edible Grain - chemistry, Edible Grain - metabolism, Gene loci, Genomes, Health risks, Humans, Laboratories, Membrane Proteins - genetics, Membrane Proteins - metabolism, Missense mutation, Mutation, Mutation, Missense, Oryza - chemistry, Oryza - genetics, Oryza - metabolism, Oryza sativa indica, Oryza sativa japonica, Phylogenetics, Phylogeny, Plant breeding, Plant Breeding - methods, Plant Roots - chemistry, Plant Roots - metabolism, Plasma, Polymorphism, Single Nucleotide, Rice, Soil Pollutants - analysis, Soil Pollutants - metabolism, Transport, Valine - genetics