Details

Autor(en) / Beteiligte

• García-Morales, Natalia
• Pérez-Aísa, Ángeles
• Fiorini, Giulia
• Tepes, Bojan
• Castro-Fernández, Manuel
• Lucendo, Alfredo
• Voynovan, Irina
• Bujanda, Luis
• Garre, Ana
• Rodrigo, Luis
• Martínez Domínguez, Samuel Jesús
• Denkovski, Maja
• Huguet Malavés, Jose M
• Jonaitis, Laimas
• Bumane, Renate
• Zaytsev, Oleg
• Mata Romero, Pilar
• Barrio, Jesús
• Fernández-Salazar, Luis
• Sarsenbaeva, Aiman Silkanovna
• Ortiz Polo, Inmaculada
• Alekseenko, Sergey
• Saracino, Ilaria Maria
• Vaira, Dino
• Keco-Huerga, Alma
• Bordin, Dmitry
• Gasbarrini, Antonio
• Lerang, Frode
• Rokkas, Theodore
• Kupčinskas, Juozas
• Leja, Marcis
• Babayeva, Gulustan
• Marcos Pinto, Ricardo
• Tonkić, Ante
• Smith, Sinead
• Phull, Perminder
• Buzas, Gyorgy M
• Simsek, Halis
• Boltin, Doron
• Gridnyev, Oleksiy
• Venerito, Marino
• Milivojevic, Vladimir
• Torà, Núria
• Cano-Català, Anna
• Moreira, Leticia
• Nyssen, Olga P
• Mégraud, Francis
• O'Morain, Colm
• Gisbert, Javier P
• Puig, Ignasi
• On Behalf Of Hp-EuReg Investigators

Titel

Helicobacter pylori Diagnostic Tests Used in Europe: Results of over 34,000 Patients from the European Registry on Helicobacter pylori Management

Ist Teil von

• Journal of clinical medicine, 2023-06, Vol.12 (13), p.4363

Ort / Verlag

Switzerland: MDPI AG

Erscheinungsjahr

2023

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Several methods are available to diagnose infection. Our objective was to evaluate the tests used for both the initial diagnosis and the confirmation of eradication after treatment in Europe. The European Registry on the management of infection is an international, multicentre, prospective, non-interventional registry aiming to evaluate the management of -infected patients in Europe. Countries with at least 100 cases registered from June 2013 to April 2021, and with a validated diagnostic method were analysed. Data were quality reviewed. A total of 34,920 adult patients from 20 countries were included (mean age 51 years; 61% women). To establish the initial diagnosis, invasive tests were performed in 19,801 (71%) patients, non-invasive in 11,369 (41%), and both in 3437 (12%). The most frequent were histology (n = 11,885; 43%), a rapid urease test (n = 10,636; 38%) and an urea breath test (n = 7577; 27%). According to the age, invasive tests were indicated in 11,179 (77%) ≥50 years, and in 8603 (65%) <50 years. Depending on the country, the use of invasive tests ranged from 29-99% in <50 years to 60-99% in ≥50. Most of the tests used to confirm eradication were non-invasive (n = 32,540; 93%), with the urea breath test being the most frequent (n = 32,540; 78%). In 2983 (9%) post-treatment tests, histology (n = 1887; 5%) or a rapid urease test (n = 1223; 4%) were performed. A great heterogeneity was observed for the initial diagnosis and confirmation of the eradication. The reasons for the apparent lack of adherence to the clinical guidelines should be further explored.