Details

Autor(en) / Beteiligte

• An, Nguyen Van
• Hai, Le Ha Long
• Luong, Vu Huy
• Vinh, Nguyen Thi Ha
• Hoa, Pham Quynh
• Hung, Le Van
• Son, Nguyen Thai
• Hong, Le Thu
• Hung, Dinh Viet
• Kien, Hoang Trung
• Le, Minh Nhat
• Viet, Nguyen Hoang
• Nguyen, Duc Hoang
• Pham, Ngai Van
• Thang, Ta Ba
• Tien, Tran Viet
• Hoang, Le Huy

Titel

Antimicrobial Resistance Patterns of Staphylococcus Aureus Isolated at a General Hospital in Vietnam Between 2014 and 2021

Ist Teil von

• Infection and drug resistance, 2024-01, Vol.17, p.259-273

Ort / Verlag

New Zealand: Dove Medical Press Limited

Erscheinungsjahr

2024

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• is a commensal bacteria species that can cause various illnesses, from mild skin infections to severe diseases, such as bacteremia. The distribution and antimicrobial resistance (AMR) pattern of varies by population, time, geographic location, and hospital wards. In this study, we elucidated the epidemiology and AMR patterns of isolated from a general hospital in Vietnam. This was a cross-sectional study. Data on all infections from 2014 to 2021 were collected from the Microbiology department of Military Hospital 103, Vietnam. Only the first isolation from each kind of specimen from a particular patient was analyzed using the Cochran-Armitage and chi-square tests. A total of 1130 individuals were diagnosed as infection. Among them, 1087 strains were tested for AMR features. Most patients with infection were in the age group of 41-65 years (39.82%). isolates were predominant in the surgery wards, and pus specimens were the most common source of isolates (50.62%). was most resistant to azithromycin (82.28%), erythromycin (82.82%), and clindamycin (82.32%) and least resistant to teicoplanin (0.0%), tigecycline (0.16%), quinupristin-dalfopristin (0.43%), linezolid (0.62%), and vancomycin (2.92%). Methicillin-resistant (MRSA) and multidrug-resistant (MDR) were prevalent, accounting for 73.02% and 60.90% of the total strains respectively, and the strains isolated from the intensive care unit (ICU) had the highest percentage of multidrug resistance (77.78%) among the wards. These findings highlight the urgent need for continuous AMR surveillance and updated treatment guidelines, particularly considering high resistance in MRSA, MDR strains, and ICU isolates. Future research focusing on specific resistant populations and potential intervention strategies is crucial to combat this rising threat.