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Therapeutic advances in infectious disease, 2019, Vol.6, p.204993611986802
2019
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Autor(en) / Beteiligte
Titel
Rapid subacute myelopathy following kidney transplantation from HTLV-1 donors: role of immunosuppresors and failure of antiretrovirals
Ist Teil von
  • Therapeutic advances in infectious disease, 2019, Vol.6, p.204993611986802
Ort / Verlag
London, England: SAGE Publications
Erscheinungsjahr
2019
Quelle
EZB Electronic Journals Library
Beschreibungen/Notizen
  • Two kidney transplant recipients from a single donor became infected with HTLV-1 (human T-lymphotropic virus type 1) in Spain. One developed myelopathy 8 months following surgery despite early prescription of antiretroviral therapy. The allograft was removed from the second recipient at month 8 due to rejection and immunosuppressors discontinued. To date, 3 years later, this patient remains infected but asymptomatic. HTLV-1 infection was recognized retrospectively in the donor, a native Spaniard who had sex partners from endemic regions. Our findings call for a reappraisal of screening policies on donor–recipient organ transplantation. Based on the high risk of disease development and the large flux of persons from HTLV-1 endemic regions, pre-transplant HTLV-1 testing should be mandatory in Spain.
Sprache
Englisch
Identifikatoren
ISSN: 2049-9361
eISSN: 2049-937X
DOI: 10.1177/2049936119868028
Titel-ID: cdi_doaj_primary_oai_doaj_org_article_d281a42520d04e758fd07ae2ba416bc6

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