Details

Autor(en) / Beteiligte

• Laenger, Florian Peter
• Schwerk, Nicolaus
• Dingemann, Jens
• Welte, Tobias
• Auber, Bernd
• Verleden, Stijn
• Ackermann, Maximilian
• Mentzer, Steven J
• Griese, Matthias
• Jonigk, Danny

Titel

Interstitial lung disease in infancy and early childhood: a clinicopathological primer

Ist Teil von

• European respiratory review, 2022-03, Vol.31 (163), p.210251

Ort / Verlag

England: European Respiratory Society

Erscheinungsjahr

2022

Quelle

MEDLINE

Beschreibungen/Notizen

• Children's interstitial lung disease (chILD) encompasses a wide and heterogeneous spectrum of diseases substantially different from that of adults. Established classification systems divide chILD into conditions more prevalent in infancy and other conditions occurring at any age. This categorisation is based on a multidisciplinary approach including clinical, radiological, genetic and histological findings. The diagnostic evaluation may include lung biopsies if other diagnostic approaches failed to identify a precise chILD entity, or if severe or refractory respiratory distress of unknown cause is present. As the majority of children will be evaluated and diagnosed outside of specialist centres, this review summarises relevant clinical, genetic and histological findings of chILD to provide assistance in clinical assessment and rational diagnostics.