Details

Autor(en) / Beteiligte

• Alberto, Florian J.
• Boyer, Frédéric
• Orozco-terWengel, Pablo
• Streeter, Ian
• Servin, Bertrand
• de Villemereuil, Pierre
• Benjelloun, Badr
• Librado, Pablo
• Biscarini, Filippo
• Colli, Licia
• Barbato, Mario
• Zamani, Wahid
• Alberti, Adriana
• Engelen, Stefan
• Stella, Alessandra
• Joost, Stéphane
• Ajmone-Marsan, Paolo
• Negrini, Riccardo
• Orlando, Ludovic
• Rezaei, Hamid Reza
• Naderi, Saeid
• Clarke, Laura
• Flicek, Paul
• Wincker, Patrick
• Coissac, Eric
• Kijas, James
• Tosser-Klopp, Gwenola
• Chikhi, Abdelkader
• Bruford, Michael W.
• Taberlet, Pierre
• Pompanon, François

Titel

Convergent genomic signatures of domestication in sheep and goats

Ist Teil von

• Nature communications, 2018-03, Vol.9 (1), p.813-9, Article 813

Ort / Verlag

London: Nature Publishing Group UK

Erscheinungsjahr

2018

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• The evolutionary basis of domestication has been a longstanding question and its genetic architecture is becoming more tractable as more domestic species become genome-enabled. Before becoming established worldwide, sheep and goats were domesticated in the fertile crescent 10,500 years before present (YBP) where their wild relatives remain. Here we sequence the genomes of wild Asiatic mouflon and Bezoar ibex in the sheep and goat domestication center and compare their genomes with that of domestics from local, traditional, and improved breeds. Among the genomic regions carrying selective sweeps differentiating domestic breeds from wild populations, which are associated among others to genes involved in nervous system, immunity and productivity traits, 20 are common to Capra and Ovis . The patterns of selection vary between species, suggesting that while common targets of selection related to domestication and improvement exist, different solutions have arisen to achieve similar phenotypic end-points within these closely related livestock species. The sheep and goat were domesticated ~10,500 years ago in the same region of the Middle-East. Here, Alberto et al compare the genomes of wild Asiatic mouflon and Bezoar ibex with that of domestics from local, traditional and improved breeds and find common targets of selection related to domestication and improvement in sheep and goats.